Norwegian professor warns about US examine on paracetamol use in pregnant girls

A Norwegian knowledgeable is skeptical of a examine that reveals 3 times the danger of some psychological problems in youngsters with excessive paracetamol use within the mom throughout being pregnant.

Professor Hedvig Marie Egeland Nordeng on the Division of Pharmacy, College of Oslo, warns towards deciphering findings and transferring them to Norwegian circumstances, based on


The brand new examine from the US was carried out on the Nationwide Institutes of Well being and is revealed within the famend journal JAMA Psychiatry. The researchers collected umbilical wire blood from 996 newborns and measured the contents and residues of the painkiller, often known as paracet in Norway. The kids had been adopted up till they had been 9 years outdated and checked for 2 psychological diagnoses.

Obvious danger
Briefly, the researchers concluded that the youngsters of the moms who had eaten essentially the most paracetamol had a 2.9 instances greater danger of getting an ADHD prognosis measured towards youngsters of moms who had used the least painkillers in being pregnant. Additionally, the danger of being identified within the so-called autism spectrum, similar to Aspergers, elevated with the consumption of extra painkillers throughout being pregnant, based on analysis.

As many as 26 % of youngsters in the US survey acquired an ADHD prognosis, which is far greater than in Norway, the place four % of youngsters have this prognosis.


Can’t be in contrast
Professor Nordeng factors out a number of elements that make her cautious. One issue is that the moms within the examine belong to the so-called Boston Beginning Cohort, the place residents typically have a special socio-economic background than Norwegians, lots of whom are extra resource-poor, poorly educated and chubby.

– Usually, we now have a more healthy meals inhabitants in Norway, says Nordeng.

Nonetheless, she finds the examine fascinating as a result of it’s based mostly on precise findings within the blood, not on self-reported consumption, which will increase uncertainty.


Nordeng additional emphasizes that her impression is that Norwegian pregnant girls are very restrictive with medicines, and have a great purpose when first taking a medication, whereas drug use is bigger amongst pregnant girls within the US than in Norway.

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